womens hair loss

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Hamilton first noted that womens androgens (testosterone, dihydrotestosterone) are necessary for the development of MPHL. The amount of androgens present does not need to be greater than normal for MPHL to occur. If androgens are present in normal amounts and the gene for hair loss is present, male pattern hair loss will occur. Axillary (under arm) and pubic hair are dependent hair on testosterone for growth. Beard growth and male pattern hair loss are dependent on dihydrotestosterone (DHT). Testosterone is converted to DHT by the enzyme, 5a loss -reductase. Finasteride (Propecia) acts by blocking this enzyme and decreasing the amount of DHT. Receptors exist on cells that bind androgens. These receptors have the greatest affinity for DHT womens followed by testosterone, estrogen, and progesterone. After binding to the receptor, DHT hair goes into the cell and interacts with the loss nucleus of the cell altering womens the production of protein by the DNA in the nucleus of the cell. Ultimately growth of the hair follicle ceases.

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Androgens (testosterone, loss dihydrotestosterone) are the most important control factors of human hair growth. Androgens must be present for the growth of beard, womens axillary (underarm), and pubic hair. Growth of scalp hair hair is loss NOT androgen-dependent but androgens are necessary for the development of male and female pattern hair loss.MALE PATTERN HAIR LOSS (Androgenetic Alopecia)It is estimated that 35 million men in the United States are affected by androgenetic alopecia. "Andro" refers to the androgens (testosterone, dihydrotestosterone) womens necessary to produce male-pattern hair loss (MPHL). "Genetic" refers to the inherited gene necessary for MPHL to occur. In men who develop MPHL the hair loss may begin any time after puberty when blood levels of androgens rise. The first change is usually recession in the temporal areas, which is seen in 96 percent of mature Caucasian males, including those men not destined to progress to further hair loss. Hamilton hair and later Norwood have classified the patterns of MPHL (See Norwood-Hamilton Scale). Although the density of hair in a given pattern of loss tends to diminish with age, there loss is no way to predict what pattern of hair womens loss a young man with early MPHL will eventually assume. In general, those who begin losing hair in the second decade are those in whom the hair loss will be the most severe. In some men, initial male-pattern hair loss may be delayed until the late third to fourth decade. It is generally recognized that men in their 20’s have a 20 percent incidence of MPHL, in their 30’s a 30 percent incidence of MPHL, in their 40’s a 40 percent incidence of MPLH, etc. Using these numbers one can see that a male hair in his 90’s has a 90 percent chance of having some degree of loss MPHL.

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womens hair loss

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